Chi, Hai;
Wan, Jiahui;
Melin, Amanda D;
DeCasien, Alex R;
Wang, Sufang;
Zhang, Yudan;
Cui, Yimeng;
... Li, Gang; + view all
(2025)
Genomic and phenotypic evidence support visual and olfactory shifts in primate evolution.
Nature Ecology and Evolution
10.1038/s41559-025-02651-5.
(In press).
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Main text 21672_3_merged_1732719822.pdf - Accepted Version Access restricted to UCL open access staff until 29 August 2025. Download (4MB) |
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Supplementary Information 21672_3_supp_258693_snm365_convrt.pdf - Accepted Version Access restricted to UCL open access staff until 29 August 2025. Download (4MB) |
Abstract
Sensory trade-offs between vision and olfaction in the evolution and radiation of primates have long been debated. However, insights have been limited by a lack of sensory gene sequences and accompanying functional predictions. Here we conduct large-scale functional analyses of visual and olfactory receptors and related brain regions across extant primates. Our results reveal a visual shift from ultraviolet to violet colour sensitivity in early haplorrhine primates, followed by acceleration in the rhodopsin retinal release rates at the origin of anthropoids, both of which are expected to greatly enhance visual acuity under brighter light conditions. Additionally, we find that the sensitivity of olfactory receptors shifted from narrowly to broadly tuned early in anthropoid evolution. In contrast, strepsirrhines appear to have retained sensitive dim-light vision and underwent functional enhancement of narrowly tuned olfactory receptors. Our models indicate that this would have enhanced odorant discrimination and facilitated olfaction-mediated physiology and behaviour. These differences in tuning patterns of olfactory receptors between major primate lineages mirror well-established morphological differences in external anatomy and brain structures, revealing new mechanisms of olfactory adaptation and evolutionary plasticity. Our multisystem analyses reveal patterns of co-evolution in genomic, molecular and neuroanatomical traits that are consistent with a sensory 'reallocation' rather than strict trade-offs.
| Type: | Article |
|---|---|
| Title: | Genomic and phenotypic evidence support visual and olfactory shifts in primate evolution |
| Location: | England |
| DOI: | 10.1038/s41559-025-02651-5 |
| Publisher version: | https://doi.org/10.1038/s41559-025-02651-5 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10206158 |
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