Cingi, C;
Bayar Muluk, N;
Mitsias, DI;
Papadopoulos, NG;
Klimek, L;
Laulajainen-Hongisto, A;
Hytönen, M;
... Scadding, GK; + view all
(2021)
The Nose as a Route for Therapy: Part 1. Pharmacotherapy.
Frontiers in Allergy
, 2
, Article 638136. 10.3389/falgy.2021.638136.
Preview |
PDF
The Nose as a Route for Therapy Part 1. Pharmacotherapy.pdf - Published Version Download (2MB) | Preview |
Abstract
This article reviews nasal structure and function in the light of intranasal pharmacotherapy. The nose provides an accessible, fast route for local treatment of nose and sinus diseases, with lower doses than are necessary systemically and few adverse effects. It can also be used for other medications as it has sufficient surface area protected from local damage by mucociliary clearance, absence of digestive enzymes, responsive blood flow, and provides a rapid route to the central nervous system.
| Type: | Article |
|---|---|
| Title: | The Nose as a Route for Therapy: Part 1. Pharmacotherapy |
| Location: | Switzerland |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3389/falgy.2021.638136 |
| Publisher version: | https://doi.org/10.3389/falgy.2021.638136 |
| Language: | English |
| Additional information: | This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | allergic rhinitis, chronic rhinosinusitis, drug delivery, intranasal route, lysine aspirin, mucociliary clearance, nasal epithelium, saline douche |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10205820 |
Archive Staff Only
 |
View Item |
