Bowler, Aislinn;
Arichi, Tomoki;
Austerberry, Chloe;
Fearon, Pasco;
Ronald, Angelica;
(2024)
A systematic review and meta-analysis of the associations between motor milestone timing and motor development in neurodevelopmental conditions.
Neuroscience and Biobehavioral Reviews
, 167
, Article 105825. 10.1016/j.neubiorev.2024.105825.
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Abstract
Early motor skills may be important early markers of neurodevelopmental conditions or predictors of their later onset. To explore this, we conducted a systematic review and meta-analysis of infant motor skill assessments in those who go on to gain a clinical diagnosis of autism, attention deficit hyperactivity disorder (ADHD), schizophrenia, language conditions, tic disorders, or developmental coordination disorder (DCD). In total, 63 articles met inclusion criteria. Three three-level meta-analyses were run. Meta-analysis of milestone achievement in N= 21205 individuals revealed gross motor milestones were significantly delayed compared to controls (g= 0.53, p< 0.001). Subgroup analyses revealed autism (g= 0.63) and DCD (g= 0.53) had the highest magnitude delays. Specific delays were revealed for holding the head up (g= 0.21), sitting (g= 0.28), standing (g= 0.35), crawling (g= 0.19), and walking (g= 0.71). Meta-analyses of standardised motor skill measurements in N= 1976 individuals revealed reduced performance compared to controls in autism and language conditions (g= −0.54, p< 0.001). Together, these findings demonstrate delayed milestone attainment and motor impairments in early childhood in neurodevelopmental conditions.
| Type: | Article |
|---|---|
| Title: | A systematic review and meta-analysis of the associations between motor milestone timing and motor development in neurodevelopmental conditions |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.neubiorev.2024.105825 |
| Publisher version: | https://doi.org/10.1016/j.neubiorev.2024.105825 |
| Language: | English |
| Additional information: | Copyright © 2024 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| Keywords: | Infant; Motor; Milestones; Walking; Sitting; Rolling; Crawling; Hold Head Up; Standing; Fine Motor; Gross Motor; Autism; ADHD; Schizophrenia; Language and Communication Disorders; Tic Disorders; Motor Disorder; DCD; Neurodevelopment disorders |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10205538 |
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