Soppe, Sarah E;
Hinton, Sharon Peacock;
Halula, Jamie C;
Lund, Jennifer L;
Baggett, Chris D;
Pruitt, Sandi L;
Mullins, Megan A;
... Thompson, Caroline A; + view all
(2025)
Registry versus claims-based index dates for studies of cancer diagnosis in administrative data.
Cancer Causes and Control
10.1007/s10552-024-01953-6.
(In press).
![[thumbnail of Index date manuscript peer reviewed.pdf]](https://discovery.ucl.ac.uk/style/images/fileicons/text.png) |
Text
Index date manuscript peer reviewed.pdf - Accepted Version Access restricted to UCL open access staff until 10 January 2026. Download (1MB) |
Abstract
PURPOSE: Studies of healthcare encounters leading to cancer diagnosis have increased over recent years. While some studies examine healthcare utilization before the cancer registry date of diagnosis, relevant pre-diagnosis interactions are not always immediately prior to this date due to date abstraction guidelines. We evaluated agreement of a registry date with a claims-based index and examined Emergency Department (ED) involvement in cancer diagnosis as an example of possible pre-diagnostic healthcare misclassification that could arise from improper date choice. METHODS: We implemented an algorithm to define a claims-based index as the date of the earliest International Classification of Diseases code for the cancer in Medicare and estimated agreement with the date of diagnosis from a North Carolina registry for patients diagnosed aged 66 or older with 16 cancer types from 2008 to 2017 (n = 92,056). We then classified whether each cancer was initially diagnosed through care originating in the ED using each date. RESULTS: The index date was identical to the cancer registry date for 47% of patients and preceded the registry date for 28%, with extent of agreement varying by cancer- and patient-specific characteristics. Agreement in ED-involved diagnosis classification using each date varied by cancer site, with sensitivity of classifications using the registry date relative to the index having a minimum of 86% for prostate and kidney cancer. CONCLUSION: Studies assessing healthcare utilization proximal to cancer diagnosis should carefully consider the relevant assessment window and be aware that the use of cancer registry versus claims-based dates may impact variable classification.
| Type: | Article |
|---|---|
| Title: | Registry versus claims-based index dates for studies of cancer diagnosis in administrative data |
| Location: | Netherlands |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1007/s10552-024-01953-6 |
| Publisher version: | https://doi.org/10.1007/s10552-024-01953-6 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions. |
| Keywords: | Diagnosis date, SEER–Medicare, Early diagnosis, Emergency diagnosis, Routes to diagnosis |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Behavioural Science and Health |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10204661 |
Loading...
Loading...Loading...Loading...Archive Staff Only
 |
View Item |
