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Variation of the Risk Associated With Potentially Modifiable Risk Factors for Dementia Between Ethnic Groups Within One Country. A Retrospective Cohort Study Using Routinely Collected Health Data in Aotearoa New Zealand

Ma'u, Etuini; Cullum, Sarah; Cheung, Gary; Tamatea, Jade; Livingston, Gill; Mukadam, Naaheed; (2025) Variation of the Risk Associated With Potentially Modifiable Risk Factors for Dementia Between Ethnic Groups Within One Country. A Retrospective Cohort Study Using Routinely Collected Health Data in Aotearoa New Zealand. International Journal of Geriatric Psychiatry , 40 (1) , Article e70042. 10.1002/gps.70042.

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Abstract

Introduction: While risk factor prevalence of individual risk factors for dementia varies between ethnic groups in New Zealand (NZ), it is not known whether the effect of these risks is the same in each group. // Methods: This retrospective cohort study identified incident cases of dementia. Cox regression models calculated the hazard ratio for dementia for each of the risk factors, after adjustment for age and sex. // Results: Education, smoking, diabetes, depression, physical activity and social isolation were associated with a 1.13–1.55 times increased risk of dementia. We did not demonstrate an association between dementia risk and hypertension, alcohol, or air pollution. Differences between ethnic groups is suggested but not confirmed due to study power. // Discussion: Differences in dementia prevention potential between ethnic groups in NZ are potentially contributed to by both differential prevalence and risk factor effects. Public health strategies must be tailored for the ethnic populations at most risk.

Type: Article
Title: Variation of the Risk Associated With Potentially Modifiable Risk Factors for Dementia Between Ethnic Groups Within One Country. A Retrospective Cohort Study Using Routinely Collected Health Data in Aotearoa New Zealand
Location: England
DOI: 10.1002/gps.70042
Publisher version: https://doi.org/10.1002/gps.70042
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Dementia, ethnicity, hazard ratio, Maori, Pacific, prevention, risk factor
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry > Mental Health of Older People
URI: https://discovery.ucl.ac.uk/id/eprint/10203797
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