Hill, William;
Weeden, Clare E;
Swanton, Charles;
(2024)
Tumor Promoters and Opportunities for Molecular Cancer Prevention.
Cancer Discovery
, 14
(7)
pp. 1154-1160.
10.1158/2159-8290.CD-24-0128.
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Abstract
Environmental carcinogens increase cancer incidence via both mutagenic and non-mutagenic mechanisms. There are over 500 known or suspected carcinogens classified by the International Agency for Research on Cancer. Sequencing of both cancerous and histologically non-cancerous tissue has been instrumental in improving our understanding of how environmental carcinogens cause cancer. Understanding how and defining which environmental or lifestyle exposures drive cancer will support cancer prevention. Recent research is revisiting the mechanisms of early tumorigenesis, paving the way for an era of molecular cancer prevention.
| Type: | Article |
|---|---|
| Title: | Tumor Promoters and Opportunities for Molecular Cancer Prevention |
| Location: | United States |
| DOI: | 10.1158/2159-8290.CD-24-0128 |
| Publisher version: | https://doi.org/10.1158/2159-8290.cd-24-0128 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Oncology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10202650 |
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