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Next generation brain health: transforming global research and public health to promote dementia prevention and risk reduction in young adult populations

Farina, Francesca; Bridgeman, Katie; Gregory, Sarah; Crivelli, Lucia; Foote, Isabelle; Jutila, Otto-Emil; Kucikova, Ludmila; ... Booi, Laura; + view all (2024) Next generation brain health: transforming global research and public health to promote dementia prevention and risk reduction in young adult populations. The Lancet Healthy Longevity , 5 (12) , Article 100665. 10.1016/j.lanhl.2024.100665. (In press). Green open access

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Abstract

Summary: Efforts to prevent dementia can benefit from precision interventions delivered to the right population at the right time; that is, when the potential to reduce risk is the highest. Young adults (aged 18–39 years) are a neglected population in dementia research and policy making despite being highly exposed to several known modifiable risk factors. The risk and protective factors that have the biggest effect on dementia outcomes in young adulthood, and how these associations differ across regions and groups, still remain unclear. To address these uncertainties, the Next Generation Brain Health team convened a multidisciplinary expert group representing 15 nations across six continents. We identified several high-priority modifiable factors in young adulthood and devised five key recommendations for promoting brain health, ranging from individual to policy levels. Increasing research and policy focus on brain health across the life course, inclusive of younger populations, is the next crucial step in the efforts to prevent dementia at the global level.

Type: Article
Title: Next generation brain health: transforming global research and public health to promote dementia prevention and risk reduction in young adult populations
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.lanhl.2024.100665
Publisher version: http://doi.org/10.1016/j.lanhl.2024.100665
Language: English
Additional information: This work is licensed under a Creative Commons License. The images or other third-party material in this article are included in the Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Population Science and Experimental Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10200316
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