Chokesuwattanaskul, A;
Penn, D;
Albero, C;
Johnson, JCS;
Benhamou, E;
Russell, LL;
Hardy, CJD;
... Warren, JD; + view all
(2024)
Inappropriate trusting behaviour in dementia.
Frontiers in Neurology
, 15
, Article 1433135. 10.3389/fneur.2024.1433135.
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Abstract
BACKGROUND: Inappropriate trusting behaviour may have significant social, financial and other consequences for people living with dementia. However, its clinical associations and predictors have not been clarified. Here we addressed this issue in canonical syndromes of frontotemporal dementia (FTD) and Alzheimer’s disease (AD). METHODS: In 34 patients with AD and 73 with FTD (27 behavioural variant (bv)FTD, 22 semantic variant primary progressive aphasia (svPPA), 24 nonfluent/agrammatic variant (nfv)PPA) we recorded inappropriate trusting and other abnormal socio-emotional behaviours using a semi-structured caregiver survey. Patients were comprehensively characterised using a general cognitive assessment and the Revised Self-Monitoring Scale (RSMS; an informant index of socioemotional awareness). RESULTS: Inappropriate trusting was more frequent in svPPA (55%) and bvFTD (44%) than nfvPPA (17%) or AD (24%). After adjusting for age, sex, education and Mini-Mental State Examination (MMSE) score, inappropriate trusting was significantly more likely in svPPA (odds ratio 3.61; 95% confidence interval 1.41–8.75) and bvFTD (3.01, 1.23–6.65) than AD. Significant predictors of inappropriate trusting comprised apathy in svPPA, disinhibition and altered pain responsiveness in bvFTD, and lower MMSE and RSMS (self-presentation) scores in AD. CONCLUSION: Dementia syndromes vary in prevalence and predictors of abnormal trusting behaviour, with implications for clinical counselling and safeguarding.
| Type: | Article |
|---|---|
| Title: | Inappropriate trusting behaviour in dementia |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3389/fneur.2024.1433135 |
| Publisher version: | http://dx.doi.org/10.3389/fneur.2024.1433135 |
| Language: | English |
| Additional information: | © 2024 Chokesuwattanaskul, Penn, Albero, Johnson, Benhamou, Russell, Hardy, Marshall, Rohrer and Warren. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/). |
| Keywords: | trust, Alzheimer’s disease, frontotemporal dementia, primary progressive aphasia, dementia |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neurodegenerative Diseases |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10197880 |
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