Banca, Paula;
Herrojo Ruiz, Maria;
Gonzalez-Zalba, Miguel Fernando;
Biria, Marjan;
Marzuki, Aleya A;
Piercy, Thomas;
Sule, Akeem;
... Robbins, Trevor W; + view all
(2024)
Action sequence learning, habits, and automaticity in obsessive-compulsive disorder.
eLife
, 12
, Article RP87346. 10.7554/elife.87346.4.
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Abstract
This study investigates the goal/habit imbalance theory of compulsion in obsessive-compulsive disorder (OCD), which postulates enhanced habit formation, increased automaticity, and impaired goal/habit arbitration. It directly tests these hypotheses using newly developed behavioral tasks. First, OCD patients and healthy participants were trained daily for a month using a smartphone app to perform chunked action sequences. Despite similar procedural learning and attainment of habitual performance (measured by an objective automaticity criterion) by both groups, OCD patients self-reported higher subjective habitual tendencies via a recently developed questionnaire. Subsequently, in a re-evaluation task assessing choices between established automatic and novel goal-directed actions, both groups were sensitive to re-evaluation based on monetary feedback. However, OCD patients, especially those with higher compulsive symptoms and habitual tendencies, showed a clear preference for trained/habitual sequences when choices were based on physical effort, possibly due to their higher attributed intrinsic value. These patients also used the habit-training app more extensively and reported symptom relief post-study. The tendency to attribute higher intrinsic value to familiar actions may be a potential mechanism leading to compulsions and an important addition to the goal/habit imbalance hypothesis in OCD. We also highlight the potential of smartphone app training as a habit reversal therapeutic tool.
| Type: | Article |
|---|---|
| Title: | Action sequence learning, habits, and automaticity in obsessive-compulsive disorder |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.7554/elife.87346.4 |
| Publisher version: | http://dx.doi.org/10.7554/elife.87346.4 |
| Language: | English |
| Additional information: | Copyright Banca et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry > Mental Health Neuroscience |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10196866 |
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