Hussein, Mohammad;
Angerud, Agnes;
Saez, Jordi;
Bogaert, Evelien;
Lemire, Matthieu;
Barry, Miriam;
Patallo, Ileana Silvestre;
... Hernandez, Victor; + view all
(2024)
Improving the modelling of a multi-leaf collimator with tilted leaf sides used in radiotherapy.
Physics and Imaging in Radiation Oncology
, 29
, Article 100543. 10.1016/j.phro.2024.100543.
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Abstract
BACKGROUND AND PURPOSE: Multi-leaf collimators (MLCs) with tilted leaf sides have a complex transmission behaviour that is not easily matched by radiotherapy treatment planning systems (TPSs). We sought to develop an MLC model that can accurately match test fields and clinically relevant plans at different centres. MATERIALS AND METHODS: Two new MLC models were developed and evaluated within a research version of a commercial TPS. Prototype I used adjusted-constant transmissions and Prototype II used variable transmissions at the tongue-and-groove and leaf-tip regions. Three different centres evaluated these prototypes for a tilted MLC and compared them with their initial MLC model using test fields and patient-specific quality-assurance measurements of clinically relevant plans. For the latter, gamma passing rates (GPR) at 2 %/2mm were recorded. RESULTS: For the prototypes the same set of MLC parameters could be used at all centres, with only a slight adjustment of the offset parameter. For centres A and C, average GPR were >95 % and within 0.5 % GPR difference between the standard, and prototype models. In center B, prototypes I and II improved the agreement in clinically relevant plans, with an increase in GPR of 2.3 % ± 0.8 % and 3.0 ± 0.8 %, respectively. CONCLUSIONS: The prototype MLC models were either similar or superior to the initial MLC model, and simpler to configure because fewer trade-offs were required. Prototype I performed comparably to the more sophisticated Prototype II and its configuration can be easily standardized, which can be useful to reduce variability and improve safety in clinical practice.
| Type: | Article |
|---|---|
| Title: | Improving the modelling of a multi-leaf collimator with tilted leaf sides used in radiotherapy |
| Location: | Netherlands |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.phro.2024.100543 |
| Publisher version: | http://dx.doi.org/10.1016/j.phro.2024.100543 |
| Language: | English |
| Additional information: | © 2024 The Author(s). Published by Elsevier B.V. on behalf of European Society of Radiotherapy & Oncology Under a Creative Commons license (http://creativecommons.org/licenses/by/4.0/). |
| Keywords: | MLC modelling, TPS modelling, TPS commissioning |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10196848 |
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