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New stable high-drug-loading amorphous solid dispersions from electrospinning

Williams, Gareth R; Majumder, Mridul; (2024) New stable high-drug-loading amorphous solid dispersions from electrospinning. Matter , 7 (8) pp. 2665-2666. 10.1016/j.matt.2024.05.014.

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Abstract

Electrospinning is a technique that can be used to fabricate amorphous solid dispersions and thus overcome the major challenge of poor drug solubility. However, the majority of studies in the literature work at relatively low drug loadings (<30% w/w). Recent work by Becelaere et al. to overcome this challenge and increase loading to >50% is discussed in this preview.

Type: Article
Title: New stable high-drug-loading amorphous solid dispersions from electrospinning
DOI: 10.1016/j.matt.2024.05.014
Publisher version: https://doi.org/10.1016/j.matt.2024.05.014
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Pharmaceutics
URI: https://discovery.ucl.ac.uk/id/eprint/10195721
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