Raisi-Estabragh, Zahra;
Szabo, Liliana;
Schuermans, Art;
Salih, Ahmed M;
Chin, Calvin WL;
Vágó, Hajnalka;
Altmann, Andre;
... Petersen, Steffen E; + view all
(2024)
Noninvasive Techniques for Tracking Biological Aging of the Cardiovascular System: JACC Family Series.
JACC: Cardiovascular Imaging
10.1016/j.jcmg.2024.03.001.
(In press).
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Abstract
Population aging is one of the most important demographic transformations of our time. Increasing the "health span"-the proportion of life spent in good health-is a global priority. Biological aging comprises molecular and cellular modifications over many years, which culminate in gradual physiological decline across multiple organ systems and predispose to age-related illnesses. Cardiovascular disease is a major cause of ill health and premature death in older people. The rate at which biological aging occurs varies across individuals of the same age and is influenced by a wide range of genetic and environmental exposures. The authors review the hallmarks of biological cardiovascular aging and their capture using imaging and other noninvasive techniques and examine how this information may be used to understand aging trajectories, with the aim of guiding individual- and population-level interventions to promote healthy aging.
Type: | Article |
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Title: | Noninvasive Techniques for Tracking Biological Aging of the Cardiovascular System: JACC Family Series |
Location: | United States |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1016/j.jcmg.2024.03.001 |
Publisher version: | https://doi.org/10.1016/j.jcmg.2024.03.001 |
Language: | English |
Additional information: | This is an Open Access article published under a Creative Commons Attribution 4.0 International (CC BY 4.0) Licence (https://creativecommons.org/licenses/by/4.0/). |
Keywords: | biological heart age, cardiac computed tomography, cardiac magnetic resonance, echocardiography, healthy aging, molecular markers, multimodality cardiovascular imaging |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
URI: | https://discovery.ucl.ac.uk/id/eprint/10191317 |




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