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Noninvasive Techniques for Tracking Biological Aging of the Cardiovascular System: JACC Family Series

Raisi-Estabragh, Zahra; Szabo, Liliana; Schuermans, Art; Salih, Ahmed M; Chin, Calvin WL; Vágó, Hajnalka; Altmann, Andre; ... Petersen, Steffen E; + view all (2024) Noninvasive Techniques for Tracking Biological Aging of the Cardiovascular System: JACC Family Series. JACC: Cardiovascular Imaging 10.1016/j.jcmg.2024.03.001. (In press). Green open access

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Abstract

Population aging is one of the most important demographic transformations of our time. Increasing the "health span"-the proportion of life spent in good health-is a global priority. Biological aging comprises molecular and cellular modifications over many years, which culminate in gradual physiological decline across multiple organ systems and predispose to age-related illnesses. Cardiovascular disease is a major cause of ill health and premature death in older people. The rate at which biological aging occurs varies across individuals of the same age and is influenced by a wide range of genetic and environmental exposures. The authors review the hallmarks of biological cardiovascular aging and their capture using imaging and other noninvasive techniques and examine how this information may be used to understand aging trajectories, with the aim of guiding individual- and population-level interventions to promote healthy aging.

Type: Article
Title: Noninvasive Techniques for Tracking Biological Aging of the Cardiovascular System: JACC Family Series
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.jcmg.2024.03.001
Publisher version: https://doi.org/10.1016/j.jcmg.2024.03.001
Language: English
Additional information: This is an Open Access article published under a Creative Commons Attribution 4.0 International (CC BY 4.0) Licence (https://creativecommons.org/licenses/by/4.0/).
Keywords: biological heart age, cardiac computed tomography, cardiac magnetic resonance, echocardiography, healthy aging, molecular markers, multimodality cardiovascular imaging
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10191317
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