Paredes, JL;
Arenas-Pinto, A;
McAlpine, C;
Matthews, R;
Milinkovic, A;
Suonpera, E;
(2024)
Depression is associated with poor self-reported adherence to antiretroviral therapy among people living with HIV attending an HIV clinic in the UK: results from a cross-sectional study.
AIDS Care
10.1080/09540121.2024.2303969.
(In press).
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Abstract
Contemporary evidence is needed to assess whether the prevalence of depression remains high among people living with HIV in the United Kingdom despite recent efforts to improve patients’ mental health, and if depression is negatively associated with individuals’ adherence to antiretroviral therapy. In a secondary analysis of a cross-sectional clinic-based survey of alcohol consumption and associated health behaviour among people living with HIV in London, of the 221 respondents, 106 (48%) had poor self-reported adherence to antiretroviral therapy (CASE Index) and 69 (31%) screened positive for depression (PHQ-9). Poor self-reported adherence to ART was 72% higher among participants who screened positive for depression in comparison with participants who screened negative. Respondents who were younger, unemployed, and reported problematic drug use were more likely to screen positive for depression. Screening and management of depression as a part of routine HIV care may support adherence to antiretroviral therapy.
| Type: | Article |
|---|---|
| Title: | Depression is associated with poor self-reported adherence to antiretroviral therapy among people living with HIV attending an HIV clinic in the UK: results from a cross-sectional study |
| Location: | England |
| DOI: | 10.1080/09540121.2024.2303969 |
| Publisher version: | http://dx.doi.org/10.1080/09540121.2024.2303969 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Science & Technology, Social Sciences, Life Sciences & Biomedicine, Health Policy & Services, Public, Environmental & Occupational Health, Psychology, Multidisciplinary, Respiratory System, Social Sciences, Biomedical, Health Care Sciences & Services, Psychology, Biomedical Social Sciences, Adherence, antiretrovirals, cross-sectional, depression, HIV, mental health, men who have sex with men, substance use, REAL-WORLD, HEALTH, INFECTION, PHQ-9 |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health > Infection and Population Health |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10191137 |
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