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Interleaved B0-mapping during dynamic Creatine-CEST for correction of temporarily fluctuating B0 inhomogeneities during plantar flexion exercise at 7T

Poblador Rodriguez, Esau; Moser, Philipp; Dymerska, Barbara; Trattnig, Siegfried; Bogner, Wolfgang; (2017) Interleaved B0-mapping during dynamic Creatine-CEST for correction of temporarily fluctuating B0 inhomogeneities during plantar flexion exercise at 7T. Presented at: ISMRM 25th Annual Meeting, Honolulu, HI, USA. Green open access

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Abstract

Once the time resolution and specificity of Cr-CEST become comparable with 31P-MRS, it may replace it for the diagnosis of muscular disorders and treatment assessment due to its superior spatial resolution and sensitivity. The need of a complete Z-spectrum acquisition for B0 inhomogeneity correction limits the achievable time resolution and is unable to track temporal ∆B0 due to subject movement or B0 field drifts that occur during a CEST experiment. Temporal B0 field tracking allows independent B0 inhomogeneity correction for each z-spectral point, which may substantially improve the reliability of spectral CEST asymmetry analysis

Type: Conference item (Presentation)
Title: Interleaved B0-mapping during dynamic Creatine-CEST for correction of temporarily fluctuating B0 inhomogeneities during plantar flexion exercise at 7T
Event: ISMRM 25th Annual Meeting
Location: Honolulu, HI, USA
Dates: 22 April 2017
Open access status: An open access version is available from UCL Discovery
Publisher version: https://cds.ismrm.org/protected/17MProceedings/PDF...
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Imaging Neuroscience
URI: https://discovery.ucl.ac.uk/id/eprint/10190791
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