Dymerska, Barbara;
Banerjee, Gargi;
Dixon, Emma;
Biondetti, Emma;
BARNES, ANNA;
Schott, Jonathan;
Fox, Nick;
... Thomas, david; + view all
(2019)
Inaccurate Visualisation of Haemorrhagic Markers in Cerebral Amyloid Angiopathy in Susceptibility Weighted Imaging can be Overcome Using Susceptibility Mapping.
Presented at: ISMRM 27th Annual Meeting & Exhibition, Montreal, QC, Canada.
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Abstract
Cerebral amyloid angiopathy is a small vessel disease characterised by imaging signatures including cerebral microbleeds and cortical superficial siderosis. We show here that non-local phase effects affecting Susceptibility Weighted Imaging (SWI) cause broadening and/or duplication of microbleeds, as well as deformation of superficial siderosis. Furthermore, susceptibility maps and “true SWI”, where local susceptibility values are used, facilitate more accurate microbleed size estimation, reduce the risk of microbleed miscount and provide better delineation of superficial siderosis. Therefore, susceptibility maps and true SWI are likely to be more accurate than SWI in identifying and grading these haemorrhagic markers, with potential clinical relevance.
| Type: | Conference item (Presentation) |
|---|---|
| Title: | Inaccurate Visualisation of Haemorrhagic Markers in Cerebral Amyloid Angiopathy in Susceptibility Weighted Imaging can be Overcome Using Susceptibility Mapping |
| Event: | ISMRM 27th Annual Meeting & Exhibition |
| Location: | Montreal, QC, Canada |
| Dates: | 11-16 May 2019 |
| Open access status: | An open access version is available from UCL Discovery |
| Publisher version: | https://archive.ismrm.org/2019/2933.html |
| Language: | English |
| Additional information: | This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Imaging Neuroscience |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10190759 |
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