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The impact of temporal signal fluctuations and susceptibility-related echo time shifts on BOLD sensitivity: an assessment in patients with brain pathologies at 7 T

Dymerska, Barbara; Cardoso, Pedro; Mahr, Nina; Matt, Eva; Fischmeister, Florian; Beisteiner, Roland; Trattnig, Siegfried; (2018) The impact of temporal signal fluctuations and susceptibility-related echo time shifts on BOLD sensitivity: an assessment in patients with brain pathologies at 7 T. Presented at: BC-ISMRM 2018, Oxford, UK. Green open access

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Abstract

Examining tSNR but ignoring regions of reduced TEₗₒ꜀ₐₗwould erroneously suggest BS sufficient to map BOLD signal changes, causing false negative results. It is thus important to consider both tSNR and TEₗₒ꜀ₐₗ in order to reliably estimate BS and to facilitate identification of potential false negative results. This is particularly true at high fields (7 T) and in patients with large pathologies.

Type: Conference item (Presentation)
Title: The impact of temporal signal fluctuations and susceptibility-related echo time shifts on BOLD sensitivity: an assessment in patients with brain pathologies at 7 T
Event: BC-ISMRM 2018
Location: Oxford, UK
Dates: September 2018
Open access status: An open access version is available from UCL Discovery
Publisher version: https://www.ismrm.org/british/2018FinalProgramme.p...
Language: English
Additional information: This version is the author-accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Imaging Neuroscience
URI: https://discovery.ucl.ac.uk/id/eprint/10190758
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