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Magnetic resonance enterography and intestinal ultrasound for the assessment and monitoring of Crohn's disease

Kumar, Shankar; De Kock, Isabelle; Blad, William; Hare, Richard; Pollok, Richard; Taylor, Stuart A; (2024) Magnetic resonance enterography and intestinal ultrasound for the assessment and monitoring of Crohn's disease. Journal of Crohn's and Colitis , Article jjae042. 10.1093/ecco-jcc/jjae042. Green open access

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Abstract

Magnetic resonance enterography (MRE) and intestinal ultrasound (IUS) have developed rapidly in the last few decades, emerging as the primary non-invasive options for both diagnosing and monitoring Crohn's disease (CD). In this review, we evaluate the pertinent data relating to the use of MRE and IUS in CD. We summarise the key imaging features of CD activity, highlight their increasing role in both the clinical and research settings, and discuss how these modalities fit within the diagnostic pathway. We discuss how they can be used to assess disease activity and treatment responsiveness, including the emergence of activity scores for standardised reporting. Additionally, we address areas of controversy such as the use of contrast agents, the role of diffusion-weighted imaging, and discuss point-of-care ultrasound. We also highlight exciting new developments including the applications of artificial intelligence. Finally, we provide suggestions for future research priorities.

Type: Article
Title: Magnetic resonance enterography and intestinal ultrasound for the assessment and monitoring of Crohn's disease
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/ecco-jcc/jjae042
Publisher version: https://doi.org/10.1093/ecco-jcc/jjae042
Language: English
Additional information: © The Author(s) 2024. Published by Oxford University Press on behalf of European Crohn’s and Colitis Organisation. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: Crohn’s disease, Inflammatory bowel disease, Intestinal ultrasound, Magnetic resonance enterography
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Department of Imaging
URI: https://discovery.ucl.ac.uk/id/eprint/10190493
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