Polman, Ricardo;
Hurst, John R;
Uysal, Omer Faruk;
Mandal, Swapna;
Linz, Dominik;
Simons, Sami;
(2024)
Cardiovascular disease and risk in COPD: a state of
the art review.
Expert Review of Cardiovascular Therapy
10.1080/14779072.2024.2333786.
(In press).
Preview |
PDF
Cardiovascular disease and risk in COPD a state of the art review.pdf - Published Version Download (2MB) | Preview |
Abstract
Introduction: Chronic Obstructive Pulmonary Disease (COPD) and cardiovascular diseases (CVD) commonly co-exist. Outcomes of people living with both conditions are poor in terms of symptom burden, receiving evidence-based treatment and mortality. Increased understanding of the underlying mechanisms may help to identify treatments to relieve this disease burden. This narrative review covers the overlap of COPD and CVD with a focus on clinical presentation, mechanisms, and interventions. Literature up to December 2023 are cited.// Areas Covered: 1. What is COPD 2. The co-existence of COPD and cardiovascular disease 3. Mechanisms of cardiovascular disease in COPD. 4. Populations with COPD are at risk of CVD 5. Complexity in the co-diagnosis of COPD in those with cardiovascular disease. 6. Therapy for COPD and implications for cardiovascular events and risk. 7. Cardiovascular risk and exacerbations of COPD. 8. Pro-active identification and management of CV risk in COPD.// Expert Opinion: The prospective identification of co-morbid COPD in CVD patients and of CVD and CV risk in people with COPD is crucial for optimizing clinical outcomes. This includes the identification of novel treatment targets and the design of clinical trials specifically designed to reduce the cardiovascular burden and mortality associated with COPD. Databases searched: Pubmed, 2006–2023.
Type: | Article |
---|---|
Title: | Cardiovascular disease and risk in COPD: a state of the art review |
Location: | England |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1080/14779072.2024.2333786 |
Publisher version: | https://doi.org/10.1080/14779072.2024.2333786 |
Language: | English |
Additional information: | © 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. |
Keywords: | COPD, arrhythmia, cardiovascular disease, cardiovascular risk, exacerbations, therapeutics |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Respiratory Medicine |
URI: | https://discovery.ucl.ac.uk/id/eprint/10190273 |
Archive Staff Only
View Item |