Johnston, R;
Sonnappa, S;
Goddings, AL;
Whittaker, E;
Segal, TY;
(2024)
A review of post COVID syndrome pathophysiology, clinical presentation and management in children and young people.
Paediatric Respiratory Reviews
10.1016/j.prrv.2024.01.002.
(In press).
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Abstract
Post Covid Syndrome (PCS) is a complex multi-system disorder with a spectrum of presentations. Severity ranges from mild to very severe with variable duration of illness and recovery. This paper discusses the difficulties defining and describing PCS. We review the current understanding of PCS, epidemiology, and predisposing factors. We consider potential mechanisms including viral persistence, clotting dysfunction and immunity. We review presentation and diagnosis and finally consider management strategies including addressing symptom burden, rehabilitation, and novel therapies.
| Type: | Article |
|---|---|
| Title: | A review of post COVID syndrome pathophysiology, clinical presentation and management in children and young people |
| Location: | England |
| DOI: | 10.1016/j.prrv.2024.01.002 |
| Publisher version: | http://dx.doi.org/10.1016/j.prrv.2024.01.002 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions. |
| Keywords: | COVID-19, Children, Fatigue, Long Covid, Paediatric, Pediatric, Post COVID, Post COVID condition, Post Covid Syndrome, Young people |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10189907 |
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