Lensen, Sarah;
Sydes, Matthew R;
Polyakov, Alex;
Wilkinson, Jack;
(2024)
When to randomize patients in a randomized controlled trial?
Fertility and Sterility
10.1016/j.fertnstert.2024.03.008.
(In press).
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Abstract
The timing of randomization should be carefully considered in the context of each trial as it has implications for the particular research question answered. In the majority of instances, randomization should be delayed until as close as practically possible to the moment of intervention. In some cases, early randomization may offer certain advantages, but trialists should balance these, including any administrative complexity or inconvenience, against the risk of avoidable protocol violations and avoidable dropout.
| Type: | Article |
|---|---|
| Title: | When to randomize patients in a randomized controlled trial? |
| Location: | United States |
| DOI: | 10.1016/j.fertnstert.2024.03.008 |
| Publisher version: | https://doi.org/10.1016/j.fertnstert.2024.03.008 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10189893 |
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