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Evidence based noninvasive presurgical evaluation for patients with drug resistant epilepsies

Trinka, E; Koepp, M; Kalss, G; Kobulashvili, T; (2024) Evidence based noninvasive presurgical evaluation for patients with drug resistant epilepsies. Current Opinion in Neurology , 37 (2) pp. 141-151. 10.1097/WCO.0000000000001253. Green open access

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Abstract

PURPOSE OF REVIEW: To review the current practices and evidence for the diagnostic accuracy and the benefits of presurgical evaluation. RECENT FINDINGS: Preoperative evaluation of patients with drug-resistant focal epilepsies and subsequent epilepsy surgery leads to a significant proportion of seizure-free patients. Even those who are not completely seizure free postoperatively often experience improved quality of life with better social integration. Systematic reviews and meta-analysis on the diagnostic accuracy are available for Video-electroencephalographic (EEG) monitoring, magnetic resonance imaging (MRI), electric and magnetic source imaging, and functional MRI for lateralization of language and memory. There are currently no evidence-based international guidelines for presurgical evaluation and epilepsy surgery. SUMMARY: Presurgical evaluation is a complex multidisciplinary and multiprofessional clinical pathway. We rely on limited consensus-based recommendations regarding the required staffing or methodological expertise in epilepsy centers.

Type: Article
Title: Evidence based noninvasive presurgical evaluation for patients with drug resistant epilepsies
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1097/WCO.0000000000001253
Publisher version: http://dx.doi.org/10.1097/wco.0000000000001253
Language: English
Additional information: This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
Keywords: Humans, Drug Resistant Epilepsy, Quality of Life, Electroencephalography, Epilepsy, Magnetic Resonance Imaging, Treatment Outcome
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Experimental Epilepsy
URI: https://discovery.ucl.ac.uk/id/eprint/10189460
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