Paramasivan, Sangeetha;
Bhan, Anant;
Rodrigues, Rashmi;
Menon, Usha;
(2024)
Trials Methodology Research: what is it and why should India invest in it?
The Lancet Regional Health - Southeast Asia
, Article 100360. 10.1016/j.lansea.2024.100360.
(In press).
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Abstract
This Viewpoint presents an overview of trials methodology research (TMR) and the case for investing in TMR in India. Randomised controlled trials and other types of clinical research inform evidence-based medicine, but this endeavour is dependent on the quality of such research. TMR is aimed at improving the way in which clinical trials are designed, conducted, analysed, and reported. The evolution of TMR in countries like the UK has been nurtured through dedicated funding support. Similar funding opportunities for TMR in India will help optimise the ethical and methodological rigour of the growing number of trials conducted in India. Such funding could help initiate an interdisciplinary network of key stakeholders in India to lead on TMR priority-setting exercises so that methodological questions of relevance to India are addressed. The establishment of trials methodology hubs will enhance initiatives such as the disease-specific clinical trials networks being set up as part of the National Biopharma Mission in India. We posit that promoting and establishing TMR as a distinct field of study in India will ensure the improvement of our health research ecosystem and call on national and international funding bodies to initiate consultation, consensus building and ringfenced funding for TMR in India.
| Type: | Article |
|---|---|
| Title: | Trials Methodology Research: what is it and why should India invest in it? |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.lansea.2024.100360 |
| Publisher version: | http://dx.doi.org/10.1016/j.lansea.2024.100360 |
| Language: | English |
| Additional information: | © 2024 The Authors. Published by Elsevier Ltd. under a Creative Commons license (http://creativecommons.org/licenses/by/4.0/). |
| Keywords: | Clinical trials, Trials methodology research, Randomised controlled trials, India |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10187317 |
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