Bordin, Nicola;
Lau, Andy M;
Orengo, Christine;
(2023)
Large-scale clustering of AlphaFold2 3D models shines light on the structure and function of proteins.
Molecular Cell
, 83
(22)
pp. 3950-3952.
10.1016/j.molcel.2023.10.039.
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Abstract
Two recent studies exploited ultra-fast structural aligners and deep-learning approaches to cluster the protein structure space in the AlphaFold Database. Barrio-Hernandez et al.1 and Durairaj et al.2 uncovered fascinating new protein functions and structural features previously unknown.
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