Gowland, A;
McGuire, E;
Goodman, AL;
(2022)
Screening for Chronic Infectious Diseases by Serology in Those Presenting with Malaria in London, United Kingdom.
American Journal of Tropical Medicine and Hygiene
, 106
(2)
pp. 661-663.
10.4269/ajtmh.20-1217.
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Abstract
The United Kingdom’s cases of malaria infection are primarily acquired in sub-Saharan Africa, with the majority of infections presenting in London.1 When patients go to a hospital with malaria, there is a screening opportunity for other geographically associated chronic infections. We identified patients who were diagnosed with malaria after presenting to our emergency department in London over a 2-year period, to assess whether there may be clinical benefit in screening for chronic viral (hepatitis B, hepatitis C, HIV) or parasitic (schistosomiasis, strongyloidiasis) infection in this cohort. Over this period, 131 patients were diagnosed with malaria. Crude seropositivity rates for HIV, hepatitis B, and strongyloidiasis were higher than expected compared with local population estimates, 7 and 28 times higher for HIV and hepatitis B, respectively. Those patients with previously unidentified cases were offered appropriate treatment. These findings support the potential clinical and public health benefits of screening for other infectious diseases in the context of a malaria diagnosis.
| Type: | Article |
|---|---|
| Title: | Screening for Chronic Infectious Diseases by Serology in Those Presenting with Malaria in London, United Kingdom |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.4269/ajtmh.20-1217 |
| Publisher version: | https://doi.org/10.4269/ajtmh.20-1217 |
| Language: | English |
| Additional information: | This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Adult, Chronic Disease, Cohort Studies, Communicable Disease Control, Communicable Diseases, Humans, London, Malaria, Mass Screening, Middle Aged, Travel-Related Illness |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10184139 |
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