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The long journey towards standards for engineering biosystems: Are the Molecular Biology and the Biotech communities ready to standardise?

Beal, J; Goñi-Moreno, A; Myers, C; Hecht, A; De Vicente, MDC; Parco, M; Schmidt, M; ... Porcar, M; + view all (2020) The long journey towards standards for engineering biosystems: Are the Molecular Biology and the Biotech communities ready to standardise? EMBO Reports , 21 (5) , Article e50521. 10.15252/embr.202050521. Green open access

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Abstract

Standards are the basis of technology: they allow rigorous description and exact measurement of properties, reliable reproducibility and a common “language” that enables different communities to work together. Molecular biology was in part created by physicists; yet, the field did not inherit the focus on the quantitation, the definition of system boundaries and the robust, unequivocal language that is characteristic of the other natural sciences. However, synthetic biology (SynBio) increasingly requires scientific, technical, operational and semantic standards for the field to become a full-fledged engineering discipline with a high level of accuracy in the design, manufacturing and performance of biological artefacts. Although the benefits of adopting standards are clear, the community is still largely reluctant to accept them, owing to concerns about adoption costs and losses in flexibility.

Type: Article
Title: The long journey towards standards for engineering biosystems: Are the Molecular Biology and the Biotech communities ready to standardise?
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.15252/embr.202050521
Publisher version: https://doi.org/10.15252/embr.202050521
Language: English
Additional information: Copyright © 2020 The Authors. Published under the terms of the CC BY NC ND 4.0 license. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Biochemical Engineering
URI: https://discovery.ucl.ac.uk/id/eprint/10183119
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