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Adult cerebral malaria: acute and subacute imaging findings, long-term clinical consequences

Coughlan, Charles; Jäger, Hans Rolf; Brealey, David; Carletti, Francesco; Hyare, Harpreet; Pattnaik, Rajyabardhan; Sahu, Praveen K; ... Checkley, Anna M; + view all (2023) Adult cerebral malaria: acute and subacute imaging findings, long-term clinical consequences. Clinical Infectious Diseases , Article ciad651. 10.1093/cid/ciad651. (In press). Green open access

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Abstract

Cerebral malaria is an important cause of mortality and neurodisability in endemic regions. We show magnetic resonance imaging (MRI) features suggestive of cytotoxic and vasogenic cerebral edema followed by microhemorrhages in 2 adult UK cases, comparing them with an Indian cohort. Long-term follow-up images correlate ongoing changes with residual functional impairment.

Type: Article
Title: Adult cerebral malaria: acute and subacute imaging findings, long-term clinical consequences
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/cid/ciad651
Publisher version: https://doi.org/10.1093/cid/ciad651
Language: English
Additional information: Copyright © The Author(s) 2023. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
Keywords: Malaria, cerebral malaria, neuro-imaging, MRI, neuro-disability
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Brain Repair and Rehabilitation
URI: https://discovery.ucl.ac.uk/id/eprint/10182390
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