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Deep learning-based detection of liver disease using MRI

Pinnock, Mark A; Hu, Yipeng; Bainbridge, Alan; Atkinson, David; Mookerjee, Rajeshwar P; Taylor, Stuart A; Barratt, Dean C; (2021) Deep learning-based detection of liver disease using MRI. In: Block, Walter F and Jones, Derek K and Boiteaux,, Sonja K, (eds.) ISMRM Annual Meeting Proceedings 2021. (pp. p. 2988). ISMRM: Concord, CA, USA. Green open access

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Abstract

Traditional approaches to MRI detection of liver disease require specialist hardware, sequences and post-processing. Here we propose a deep learning (DL) based model for the detection of liver disease using standard T2-weighted anatomical sequences, as an early feasibility study for the potential of DL-based classification of liver disease severity. Our DL model achieved a diagnostic accuracy of 0.92 on unseen data and achieved a test accuracy of 0.75 when trained with relevant anatomical segmentation masks without images, demonstrating potential scanner/sequence independence. Lastly, we used DL interpretability techniques to analyse failure cases.

Type: Proceedings paper
Title: Deep learning-based detection of liver disease using MRI
Event: 2021 ISMRM & SMRT Annual Meeting & Exhibition
Location: online
Dates: 15 May 2021 - 20 May 2021
Open access status: An open access version is available from UCL Discovery
Publisher version: https://archive.ismrm.org/2021/2988.html
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Department of Imaging
URI: https://discovery.ucl.ac.uk/id/eprint/10178914
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