Rothwell, John;
Antal, Andrea;
Burke, David;
Carlsen, Antony;
Georgiev, Dejan;
Jahanshahi, Marjan;
Sternad, Dagmar;
... Ziemann, Ulf; + view all
(2021)
Central nervous system physiology.
Clinical Neurophysiology
, 132
(12)
pp. 3043-3083.
10.1016/j.clinph.2021.09.013.
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Abstract
This is the second chapter of the series on the use of clinical neurophysiology for the study of movement disorders. It focusses on methods that can be used to probe neural circuits in brain and spinal cord. These include use of spinal and supraspinal reflexes to probe the integrity of transmission in specific pathways; transcranial methods of brain stimulation such as transcranial magnetic stimulation and transcranial direct current stimulation, which activate or modulate (respectively) the activity of populations of central neurones; EEG methods, both in conjunction with brain stimulation or with behavioural measures that record the activity of populations of central neurones; and pure behavioural measures that allow us to build conceptual models of motor control. The methods are discussed mainly in relation to work on healthy individuals. Later chapters will focus specifically on changes caused by pathology.
| Type: | Article |
|---|---|
| Title: | Central nervous system physiology |
| Location: | Netherlands |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.clinph.2021.09.013 |
| Publisher version: | https://doi.org/10.1016/j.clinph.2021.09.013 |
| Language: | English |
| Additional information: | Copyright © 2021 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
| Keywords: | Transcranial magnetic stimulation; Transcranial direct current stimulation; Evoked potential; Reaction time; Bereitschaftspotential; Computational motor control |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Movement Neurosciences |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10178846 |
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