Coughlan, Charles;
Lim, Emma;
Chandratheva, Arvind;
Jager, Rolf;
Werring, David J;
(2023)
Cerebral amyloid angiopathy-related inflammation: a rare but important cause of acute confusion on the general medical take.
British Journal of Hospital Medicine
, 84
(8)
10.12968/hmed.2023.0102.
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Abstract
Cerebral amyloid angiopathy is a common small vessel disease caused by abnormal protein deposition within cerebral blood vessels. In the last 20 years, improved diagnostics have implicated cerebral amyloid angiopathy in the pathophysiology of intracerebral haemorrhage. Cerebral amyloid angiopathy is relevant to general medical doctors, as it can cause transient focal neurological episodes (‘amyloid spells’) which mimic seizures and transient ischaemic attacks; it also has a significant bearing on anticoagulation decisions. With the ageing population, general medics are more likely to encounter patients with cerebral amyloid angiopathy. This case highlights an important cause of confusion related to cerebral amyloid angiopathy in an older adult presenting on the general medical take.
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