Veyckemans, Francis;
Sola, Chrystelle;
De Graaff, Jurgen C;
Becke-Jakob, Karin;
Zielinska, Marzena;
Hansen, Tom G;
Walker, Suellen M;
... Habre, Walid; + view all
(2023)
Epidemiology and outcomes of inguinal surgery with or without regional anaesthesia in neonates and small infants: A subanalysis of the NECTARINE database.
European Journal of Anaesthesiology (EJA)
, 40
(12)
pp. 956-959.
10.1097/eja.0000000000001870.
Preview |
Text
Walker_Short scientific report epidemiology and outcomes of inguinal surgery with or without regional anaesthesia in neonates and small infants.pdf Download (146kB) | Preview |
Abstract
The use of regional anaesthesia, whenever feasible, is often recommended in neonates and small infants undergoing superficial surgery either to avoid general anaesthesia or to reduce the depth of general anaesthesia, when given in conjunction with regional anaesthesia (GAR). The aims are to reduce exposure to general anaesthesia agents and its potential neurodevelopmental consequences if any, decrease the risk of postoperative apnoea, and decrease the risks associated with tracheal intubation (difficulties, hypoxaemia, laryngotracheal morbidity) and controlled ventilation. Except for the results of the GAS study,1 there are little data on the associated critical events and outcomes. The NECTARINE study2 revealed a trend towards fewer interventions for critical events when regional anaesthesia or GAR was used in comparison with general anaesthesia alone. However, these results were generated from the whole cohort of infants independent of the types of surgery and including cases of local anaesthetic infiltration of the wound. To draw more precise conclusions on the potential beneficial role of regional anaesthesia and/or GAR, we performed a secondary analysis of the data excluding the local infiltration cases and compared the results in infants undergoing the same procedures. The main outcome was to evaluate the incidence of interventions in response to predefined peri-operative severe critical events in neonates and infants undergoing the same surgery with regional anaesthesia alone, GAR or general anaesthesia alone. The secondary outcomes were morbidity and mortality at 30 days.
| Type: | Article |
|---|---|
| Title: | Epidemiology and outcomes of inguinal surgery with or without regional anaesthesia in neonates and small infants: A subanalysis of the NECTARINE database |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1097/eja.0000000000001870 |
| Publisher version: | https://doi.org/10.1097/eja.0000000000001870 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Neurosciences Dept |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10177554 |
Archive Staff Only
 |
View Item |
