Llorente, Isaac;
Oxtoby, Neil;
(2021)
Correction of AV-1451 tau-PET signal.
Presented at: New Horizons in Alzheimer's Disease (NHAD 2021), Leuven, Belgium.
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Abstract
The current method of normalising the AV1451 tau-PET signal is shown to lack a consistency in CN paired scans that we do not attribute to random noise. Data exploration shows how multiple reference regions could be used to achieve better consistency within scans, improving the signal-to-noise ratio (SNR). Additionally, due to the different behaviour of subcortical regions in the brain, the new method could see some improvement by adjusting to each region. Studies based on this radiotracer might benefit from selecting a subset of regions with a higher SNR.
| Type: | Poster |
|---|---|
| Title: | Correction of AV-1451 tau-PET signal |
| Event: | New Horizons in Alzheimer's Disease (NHAD 2021) |
| Location: | Leuven, Belgium |
| Dates: | 27 - 28 October 2021 |
| Open access status: | An open access version is available from UCL Discovery |
| Publisher version: | https://www.vibconferences.be/sites/default/files/... |
| Language: | English |
| Keywords: | AV1451, tau-PET, Alzheimer, SUVR, reference region, signal correction |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10177301 |
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