Moseley, Philip;
Bamford, Alasdair;
Eisen, Sarah;
Lyall, Hermione;
Kingston, Margaret;
Thorne, Claire;
Piñera, Cecilia;
... Kadambari, Seilesh; + view all
(2024)
Resurgence of congenital syphilis: new strategies against an old foe.
The Lancet Infectious Diseases
, 24
(1)
e24-e35.
10.1016/S1473-3099(23)00314-6.
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Abstract
Congenital syphilis is a major global cause of fetal loss, stillbirth, neonatal death, and congenital infection. In 2020, the global rate of congenital syphilis was 425 cases per 100 000 livebirths-substantially higher than WHO's elimination target of 50 cases per 100 000 livebirths. Case rates are rising in many high-income countries, but remain low compared with those in low-income and middle-income settings. This Review aims to summarise the current epidemiology and knowledge on transmission and treatment of syphilis in pregnancy, and proposes measures to reduce the rising incidence seen worldwide. We also describe emerging diagnostic and treatment tools to prevent vertical transmission and improve management of congenital syphilis. Finally, we outline a programme of public health priorities, which include research, clinical, and preventive strategies.
| Type: | Article |
|---|---|
| Title: | Resurgence of congenital syphilis: new strategies against an old foe |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/S1473-3099(23)00314-6 |
| Publisher version: | https://doi.org/10.1016/S1473-3099(23)00314-6 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10176490 |
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