Ong, Hon Shing;
Dart, John K;
Mehta, Jodhbir S;
(2021)
A Review of Clinical Disease Scoring Systems for Cicatricial Diseases of the Conjunctiva.
Frontiers in Medicine
, 8
, Article 664572. 10.3389/fmed.2021.664572.
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Abstract
Cicatricial conjunctival diseases (CCDs), are a diverse group of ocular surface diseases characterized by chronic scarring of the conjunctiva. These diseases can cause significant ocular morbidity. They are life-long once acquired and can be debilitating, painful diseases leading to visual loss. A recent international consensus of ocular surface disease experts have placed emphasis on the need of validated clinical disease scoring systems for CCDs, important for the objective evaluation of disease severity, outcomes of therapies, and longitudinal monitoring of disease. This review aims to describe the various published clinical disease scoring systems available for CCDs and evaluates the benefits and limitations of each system. It can be used as a guide for clinicians managing patients with CCDs and for researchers evaluating potential therapies in clinical trials.
| Type: | Article |
|---|---|
| Title: | A Review of Clinical Disease Scoring Systems for Cicatricial Diseases of the Conjunctiva |
| Location: | Switzerland |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3389/fmed.2021.664572 |
| Publisher version: | https://doi.org/10.3389/fmed.2021.664572 |
| Language: | English |
| Additional information: | Copyright © 2021 Ong, Dart and Mehta. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
| Keywords: | cicatrising conjunctivitis, cicatricial conjunctival diseases, conjunctiva, scarring, fornix depth, grading, mucous membrane pemphigoid, Stevens-Johnson Syndrome |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10176420 |
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