Morkuniene, Ruta;
Cole, Tim J;
Jakimaviciene, Egle Marija;
Bankauskiene, Agne;
Isakova, Jelena;
Drazdiene, Nijole;
Basys, Vytautas;
(2023)
Regional references vs. international standards for assessing weight and length by gestational age in Lithuanian neonates.
Frontiers in Pediatrics
, 11
, Article 1173685. 10.3389/fped.2023.1173685.
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Abstract
INTRODUCTION: There is no global consensus as to which standards are the most appropriate for the assessment of birth weight and length. The study aimed to compare the applicability of regional and global standards to the Lithuanian newborn population by sex and gestational age, based on the prevalence of small or large for gestational age (SGA/LGA). MATERIALS AND METHODS: Analysis was performed on neonatal length and weight data obtained from the Lithuanian Medical Birth Register from 1995 to 2015 (618,235 newborns of 24-42 gestational weeks). Their distributions by gestation and sex were estimated using generalized additive models for location, scale, and shape (GAMLSS), and the results were compared with the INTERGROWTH-21st (IG-21) standard to evaluate the prevalence of SGA/LGA (10th/90th centile) at different gestational ages. RESULTS: The difference in median length at term between the local reference and IG-21 was 3 cm-4 cm, while median weight at term differed by 200 g. The Lithuanian median weight at term was higher than in IG-21 by a full centile channel width, while the median length at term was higher by two channel widths. Based on the regional reference, the prevalence rates of SGA/LGA were 9.7%/10.1% for boys and 10.1%/9.9% for girls, close to the nominal 10%. Conversely, based on IG-21, the prevalence of SGA in boys/girls was less than half (4.1%/4.4%), while the prevalence of LGA was double (20.7%/19.1%). DISCUSSION: Regional population-based neonatal references represent Lithuanian neonatal weight and length much more accurately than the global standard IG-21 which provides the prevalence rates for SGA/LGA that differ from the true values by a factor of two.
| Type: | Article |
|---|---|
| Title: | Regional references vs. international standards for assessing weight and length by gestational age in Lithuanian neonates |
| Location: | Switzerland |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3389/fped.2023.1173685 |
| Publisher version: | https://doi.org/10.3389/fped.2023.1173685 |
| Language: | English |
| Additional information: | © 2023 Morkuniene, Cole, Jakimaviciene, Bankauskiene, Isakova, Drazdiene, Basys and Tutkuviene. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
| Keywords: | LGA (large for gestational age), SGA (small for gestational age), birth, global, growth charts, newborns, preterm (birth), regional |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10173838 |
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