Xing, Yongzheng;
Rottensteiner, Alexia;
Ciccone, Jonah;
Howorka, Stefan;
(2023)
Functional Nanopores Enabled with DNA.
Angewandte Chemie International Edition
, Article e202303103. 10.1002/anie.202303103.
(In press).
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Abstract
Membrane-spanning nanopores are used in label-free single-molecule sensing and next-generation portable nucleic acid sequencing, and as powerful research tools in biology, biophysics, and synthetic biology. Naturally occurring protein and peptide pores, as well as synthetic inorganic nanopores, are used in these applications, with their limitations. The structural and functional repertoire of nanopores can be considerably expanded by functionalising existing pores with DNA strands and by creating an entirely new class of nanopores with DNA nanotechnology. This review outlines progress in this area of functional DNA nanopores and outlines developments to open up new applications.
| Type: | Article |
|---|---|
| Title: | Functional Nanopores Enabled with DNA |
| Location: | Germany |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1002/anie.202303103 |
| Publisher version: | https://doi.org/10.1002/anie.202303103 |
| Language: | English |
| Additional information: | © 2023 The Authors. Angewandte Chemie International Edition published by Wiley-VCH GmbH This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | DNA, DNA Nanotechnology, Nanopore, Nanostructure, Self-Assembly |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Chemistry |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10171042 |
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