Lioliou, G;
Navarrete-Leon, C;
Astolfo, A;
Savvidis, S;
Bate, D;
Endrizzi, M;
Hagen, CK;
(2023)
A laboratory-based beam tracking x-ray imaging method achieving two-dimensional phase sensitivity and isotropic resolution with unidirectional undersampling.
Scientific Reports
, 13
, Article 8707.
Preview |
Text
Olivo_s41598-023-35901-2.pdf Download (4MB) | Preview |
Abstract
Beam tracking X-ray Phase Contrast Imaging is a “Shack-Hartmann” type approach which uses a pre-sample mask to split the x-rays into “beamlets” which are interrogated by a detector with sufficient resolution. The ultimate spatial resolution is determined by the size of the mask apertures, however achieving this resolution level requires “stepping” the sample or the mask in increments equal to the aperture size (“dithering”). If an array of circular apertures is used (which also provides two-dimensional phase sensitivity) instead of long parallel slits, this stepping needs to be carried out in two directions, which lengthens scan times significantly. We present a mask design obtained by offsetting rows of circular apertures, allowing for two-dimensional sensitivity and isotropic resolution while requiring sample or mask stepping in one direction only. We present images of custom-built phantoms and biological specimens, demonstrating that quantitative phase retrieval and near aperture-limited spatial resolutions are obtained in two orthogonal directions.
| Type: | Article |
|---|---|
| Title: | A laboratory-based beam tracking x-ray imaging method achieving two-dimensional phase sensitivity and isotropic resolution with unidirectional undersampling |
| Open access status: | An open access version is available from UCL Discovery |
| Publisher version: | https://doi.org/10.1038/s41598-023-35901-2 |
| Language: | English |
| Additional information: | © The Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
| Keywords: | Biomedical engineering, Imaging techniques, X-rays |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10170822 |
Archive Staff Only
 |
View Item |
