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Lecanemab trial in AD brings hope but requires greater clarity

Thambisetty, Madhav; Howard, Robert; (2023) Lecanemab trial in AD brings hope but requires greater clarity. Nature Reviews Neurology , 19 pp. 132-133. 10.1038/s41582-022-00768-w. Green open access

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Abstract

The phase III Clarity AD clinical trial of lecanemab, an amyloid-targeting antibody, showed a small clinical beneft in people with Alzheimer disease. However, several questions remain regarding the true clinical relevance, safety and accessibility of lecanemab in this patient population

Type: Article
Title: Lecanemab trial in AD brings hope but requires greater clarity
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1038/s41582-022-00768-w
Publisher version: https://doi.org/10.1038/s41582-022-00768-w
Language: English
Additional information: This version is the author-accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry > Mental Health of Older People
URI: https://discovery.ucl.ac.uk/id/eprint/10169118
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