Freemantle, Nick;
Myers, Patrick O;
Siepe, Matthias;
(2023)
Do all roads lead to Rome? Critical reassessment of the individual patient meta-analysis on bypass grafts by Gaudino et al.
European Journal of Cardio-Thoracic Surgery
, 63
(1)
, Article ezac564. 10.1093/ejcts/ezac564.
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Commentary to Gaudino et al 061122.pdf - Accepted Version Download (676kB) | Preview |
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Abstract
INTRODUCTION The recent individual patient data meta-analysis by Gaudino et al. [1], comparing outcomes with different grafts for coronary artery surgery from not for this question-randomized trials, was met with questions on the methodology given that some of the results proved controversial. The EJCTS reacted to various comments on the methodology and suggested an independent reanalysis of the data. The author group of the paper, led by Mario Gaudino, should be applauded for their scientifically sound cooperation in this exercise. In the spirit of open data and open science, the authors shared their entire dataset and the codes with the journal. The authors of this Editorial wish to express their gratitude and esteem for this behaviour, which exemplifies excellence in science. The journal was particularly keen to have this process initiated because the topic is important, and the main players have considerable expertise in CABG research and statistics.
| Type: | Article |
|---|---|
| Title: | Do all roads lead to Rome? Critical reassessment of the individual patient meta-analysis on bypass grafts by Gaudino et al. |
| Location: | Germany |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1093/ejcts/ezac564 |
| Publisher version: | https://doi.org/10.1093/ejcts/ezac564 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Science & Technology, Life Sciences & Biomedicine, Cardiac & Cardiovascular Systems, Respiratory System, Surgery, Cardiovascular System & Cardiology, Bypass grafts, CABG, Radial artery, Sapheneous vein, Mammarian artery, Meta-analysis |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > Comprehensive CTU at UCL |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10163987 |
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