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Biomodifying the 'natural': from Adaptive Regulation to Adaptive Societal Governance

Mourby, Miranda; Bell, Jessica; Morrison, Michael; Faulkner, Alex; Li, Phoebe; Bicudo, Edison; Webster, Andrew; (2022) Biomodifying the 'natural': from Adaptive Regulation to Adaptive Societal Governance. Journal of Law and the Biosciences , 9 (1) , Article lsac018. 10.1093/jlb/lsac018. Green open access

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Abstract

Biomodifying technologies-such as gene editing, induced pluripotent stem cells, and bioprinting-are being developed for a wide range of applications, from pest control to lab-grown meat. In medicine, regulators have responded to the challenge of evaluating modified 'natural' material as a therapeutic 'product' by introducing more flexible assessment schemes. Attempts have also been made to engage stakeholders across the globe on the acceptable parameters for these technologies, particularly in the case of gene editing. Regulatory flexibility and stakeholder engagement are important, but a broader perspective is also needed to respond to the potential disruption of biomodification. Our case-study technologies problematize basic ideas-such as 'nature', 'product', and 'donation'-that underpin the legal categories used to regulate biotechnology. Where such foundational concepts are rendered uncertain, a socially responsive and sustainable solution would involve exploring evolutions in these concepts across different societies. We suggest that the global observatory model is a good starting point for this 'Adaptive Societal Governance' approach, in which a self-organizing network of scholars and interested parties could carry out the multi-modal (meta)analyses needed to understand societal constructions of ideas inherent to our understanding of 'life'.

Type: Article
Title: Biomodifying the 'natural': from Adaptive Regulation to Adaptive Societal Governance
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/jlb/lsac018
Publisher version: https://doi.org/10.1093/jlb/lsac018
Language: English
Additional information: © The Author(s) 2022. Published by Oxford University Press on behalf of Duke University School of Law, Harvard Law School, Oxford University Press, and Stanford Law School. This is an Open Access article distributed under theterms oftheCreativeCommons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: Social Sciences, Science & Technology, Life Sciences & Biomedicine, Ethics, Law, Medical Ethics, Medicine, Legal, Social Sciences - Other Topics, Government & Law, Legal Medicine, synthetic biology, regenerative medicine, Adaptive Governance, REGENERATIVE MEDICINE, MITOCHONDRIAL, LEGISLATION, CHALLENGES, IDENTITY, MARKET, BLOOD
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > STEaPP
URI: https://discovery.ucl.ac.uk/id/eprint/10163697
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