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Social inequality and the syndemic of chronic disease and COVID-19: County-level analysis in the USA

Islam, N; Lacey, B; Shabnam, S; Erzurumluoglu, AM; Dambha-Miller, H; Chowell, G; Kawachi, I; (2021) Social inequality and the syndemic of chronic disease and COVID-19: County-level analysis in the USA. Journal of Epidemiology and Community Health , 75 (6) pp. 496-500. 10.1136/jech-2020-215626. Green open access

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Abstract

BACKGROUND: Given the effect of chronic diseases on risk of severe COVID-19 infection, the present pandemic may have a particularly profound impact on socially disadvantaged counties. METHODS: Counties in the USA were categorised into five groups by level of social vulnerability, using the Social Vulnerability Index (a widely used measure of social disadvantage) developed by the US Centers for Disease Control and Prevention. The incidence and mortality from COVID-19, and the prevalence of major chronic conditions were calculated relative to the least vulnerable quintile using Poisson regression models. RESULTS: Among 3141 counties, there were 5 010 496 cases and 161 058 deaths from COVID-19 by 10 August 2020. Relative to the least vulnerable quintile, counties in the most vulnerable quintile had twice the rates of COVID-19 cases and deaths (rate ratios 2.11 (95% CI 1.97 to 2.26) and 2.42 (95% CI 2.22 to 2.64), respectively). Similarly, the prevalence of major chronic conditions was 24%–41% higher in the most vulnerable counties. Geographical clustering of counties with high COVID-19 mortality, high chronic disease prevalence and high social vulnerability was found, especially in southern USA. CONCLUSIONS: Some counties are experiencing a confluence of epidemics from COVID-19 and chronic diseases in the context of social disadvantage. Such counties are likely to require enhanced public health and social support.

Type: Article
Title: Social inequality and the syndemic of chronic disease and COVID-19: County-level analysis in the USA
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1136/jech-2020-215626
Publisher version: http://dx.doi.org/10.1136/jech-2020-215626
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
URI: https://discovery.ucl.ac.uk/id/eprint/10161566
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