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The International League Against Epilepsy New Classification of Neonatal Seizures

Mizrahi, Eli M; Pressler, Ronit M; (2022) The International League Against Epilepsy New Classification of Neonatal Seizures. Pediatrics , 150 (5) , Article e2022058114. 10.1542/peds.2022-058114. Green open access

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Abstract

Clinical recognition has been the cornerstone of the diagnosis and management of neonatal seizures from the earliest days of care for affected infants, and previous classification systems have been based on these bedside observations. Recently, the Task Force on Neonatal Seizures of the International League Against Epilepsy (ILAE) published a new classification system that has significant implications for the care of newborns suspected of seizures. This new construct includes electroencephalographic (EEG) confirmation rather than reliance solely on clinical observation of seizures.1 For some newborns, it will improve diagnosis and management that may affect long-term neurodevelopmental outcomes. For others, it may emphasize additional disparities in health care requiring new clinical strategies. Here, we discuss the rationale for the development of this new classification, advantages and limitations, potential impact, and new strategies for resource-challenged care centers.

Type: Article
Title: The International League Against Epilepsy New Classification of Neonatal Seizures
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1542/peds.2022-058114
Publisher version: https://doi.org/10.1542/peds.2022-058114
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Infant, Newborn, Humans, Seizures, Epilepsy, Infant, Newborn, Diseases
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Neurosciences Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10160434
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