Bayford, R;
Damaso, R;
Jiang, D;
Rahal, M;
Demosthenous, A;
(2022)
Development of a Biosensor for fast point-of-care Blood Analysis of Troponin.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
, 2022
pp. 910-913.
10.1109/EMBC48229.2022.9871851.
Preview |
Text
Development of a Biosensor for fast point-of-care Blood Analysis of Troponin_Mod_Final.pdf - Accepted Version Download (429kB) | Preview |
Abstract
We present the development of novel tetrapolar EIS biosensor for the detect of troponin. Troponin has considerable diagnostic power and provide invaluable prognostic information for risk stratification. of acute coronary syndromes. Clinical Relevance- A feasibility study was undertaken to assess the diagnostic performance of serial cardiac troponin measurements which is excellent as these structural proteins are unique to the heart and thus sensitive and specific of damage to the myocardium. clinical molecular diagnostics and home healthcare. Troponin's biosensors would provide point-of-care and rapid decision making for the early detection of CS. Clinically relevant window of cTnI testing, concentrations from 10pM to 0.1μM were achieved.
| Type: | Article |
|---|---|
| Title: | Development of a Biosensor for fast point-of-care Blood Analysis of Troponin |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1109/EMBC48229.2022.9871851 |
| Publisher version: | https://doi.org/10.1109/EMBC48229.2022.9871851 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Biomarkers, Biosensing Techniques, Hematologic Tests, Point-of-Care Systems, Troponin I |
| UCL classification: | UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Electronic and Electrical Eng UCL > Provost and Vice Provost Offices > UCL BEAMS UCL |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10157944 |
Archive Staff Only
 |
View Item |
