Miyamoto, Kentaro;
Trudel, Nadescha;
Kamermans, Kevin;
Lim, Michele C;
Lazari, Alberto;
Verhagen, Lennart;
Wittmann, Marco K;
(2021)
Identification and disruption of a neural mechanism for accumulating prospective metacognitive information prior to decision-making.
Neuron
, 109
(8)
1396-1408.e7.
10.1016/j.neuron.2021.02.024.
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Abstract
More than one type of probability must be considered when making decisions. It is as necessary to know one's chance of performing choices correctly as it is to know the chances that desired outcomes will follow choices. We refer to these two choice contingencies as internal and external probability. Neural activity across many frontal and parietal areas reflected internal and external probabilities in a similar manner during decision-making. However, neural recording and manipulation approaches suggest that one area, the anterior lateral prefrontal cortex (alPFC), is highly specialized for making prospective, metacognitive judgments on the basis of internal probability; it is essential for knowing which decisions to tackle, given its assessment of how well they will be performed. Its activity predicted prospective metacognitive judgments, and individual variation in activity predicted individual variation in metacognitive judgments. Its disruption altered metacognitive judgments, leading participants to tackle perceptual decisions they were likely to fail.
| Type: | Article |
|---|---|
| Title: | Identification and disruption of a neural mechanism for accumulating prospective metacognitive information prior to decision-making |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.neuron.2021.02.024 |
| Publisher version: | https://doi.org/10.1016/j.neuron.2021.02.024 |
| Language: | English |
| Additional information: | © 2021 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| Keywords: | Prospective metacognition, decision-making, anterior lateral prefrontal cortex, functional magnetic resonance imaging, transcranial magnetic stimulation |
| UCL classification: | UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10157424 |
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