Biguri, Ander;
Kotasidis, Fotis;
Whitehead, Alexander C;
Burger, Irene;
Hutton, Brian F;
Thielemans, Kris;
(2021)
Systematic Evaluation of the Impact of Involuntary Motion in Whole Body Dynamic PET.
In:
2021 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC).
IEEE: Piscataway, NJ, USA.
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Abstract
Involuntary patient motion can happen in dynamic whole body (DWB) PET due to long scanning times, which may cause inaccurate quantification of tissue parameters. To quantify the impact on Patlak parameters, we simulated dynamic data using patient-derived motion fields, systematically introducing the motion at different passes of the dynamic scan, both inter and intra-frame. Estimated parameters are compared against the ground truth. Results show that errors can be large, even for small motion. Caution is advised when quantitatively evaluating DWB-PET images, if any motion has been detected.
| Type: | Proceedings paper |
|---|---|
| Title: | Systematic Evaluation of the Impact of Involuntary Motion in Whole Body Dynamic PET |
| Event: | 2021 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) |
| Dates: | 16 Oct 2021 - 23 Oct 2021 |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1109/nss/mic44867.2021.9875689 |
| Publisher version: | http://dx.doi.org/10.1109/nss/mic44867.2021.987568... |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Systematics, Dynamics, Biomedical imaging |
| UCL classification: | UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Chemical Engineering UCL > Provost and Vice Provost Offices > UCL BEAMS UCL |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10156723 |
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