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How Do I Find Clues About Where Myoclonus Is Originating?

Latorre, Anna; Hale, Blake; Rocchi, Lorenzo; (2022) How Do I Find Clues About Where Myoclonus Is Originating? Movement Disorders Clinical Practice , 9 (5) pp. 721-722. 10.1002/mdc3.13472. Green open access

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Abstract

Myoclonus is defined as a brief and jerky shock-like involuntary movement caused by abrupt muscle contraction or sudden cessation of ongoing muscular activity. Myoclonus can be generated by abnormal activity in different parts of the nervous system, both peripheral and central, including cortical and subcortical structures. According to the presumed neural generator, myoclonus is classified as cortical, subcortical (including myoclonus-dystonia and brainstem/reticular myoclonus), spinal (including segmental spinal and propriospinal myoclonus), and peripheral. The identification of myoclonus subtypes, and therefore its potential source, is clinically important because it can guide diagnosis and treatment. In this video lecture (Video), we reviewed how to determine myoclonus origin. We first reviewed the clinical features typical of each myoclonus subtype. We, then, explored the electrophysiological techniques that can aid in the differential diagnosis of myoclonus, based on its origin. In conclusion, we provided a clinical and electrophysiological overview on how to find clues about neural generators of myoclonus.

Type: Article
Title: How Do I Find Clues About Where Myoclonus Is Originating?
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/mdc3.13472
Publisher version: https://doi.org/10.1002/mdc3.13472
Language: English
Additional information: © 2022 The Authors. Movement Disorders Clinical Practice published by Wiley Periodicals LLC on behalf of Movement Disorder Society. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Keywords: Science & Technology, Life Sciences & Biomedicine, Clinical Neurology, Neurosciences & Neurology, myoclonus, cortical myoclonus, brainstem myoclonus, electrophysiology, propriospinal myoclonus, spinal myoclonus
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical Neuroscience
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
URI: https://discovery.ucl.ac.uk/id/eprint/10156597
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