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Meta-registration: Learning Test-Time Optimization for Single-Pair Image Registration

Baum, Zachary MC; Hu, Yipeng; Barratt, Dean C; (2022) Meta-registration: Learning Test-Time Optimization for Single-Pair Image Registration. In: International Workshop on Advances in Simplifying Medical Ultrasound ASMUS 2022: Simplifying Medical Ultrasound. (pp. pp. 162-171). Springer, Cham Green open access

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Abstract

Neural networks have been proposed for medical image registration by learning, with a substantial amount of training data, the optimal transformations between image pairs. These trained networks can further be optimized on a single pair of test images - known as test-time optimization. This work formulates image registration as a meta-learning algorithm. Such networks can be trained by aligning the training image pairs while simultaneously improving test-time optimization efficacy; tasks which were previously considered two independent training and optimization processes. The proposed meta-registration is hypothesized to maximize the efficiency and effectiveness of the test-time optimization in the “outer” meta-optimization of the networks. For image guidance applications that often are time-critical yet limited in training data, the potentially gained speed and accuracy are compared with classical registration algorithms, registration networks without meta-learning, and single-pair optimization without test-time optimization data. Experiments are presented in this paper using clinical transrectal ultrasound image data from 108 prostate cancer patients. These experiments demonstrate the effectiveness of a meta-registration protocol, which yields significantly improved performance relative to existing learning-based methods. Furthermore, the meta-registration achieves comparable results to classical iterative methods in a fraction of the time, owing to its rapid test-time optimization process.

Type: Proceedings paper
Title: Meta-registration: Learning Test-Time Optimization for Single-Pair Image Registration
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/978-3-031-16902-1_16
Publisher version: https://doi.org/10.1007/978-3-031-16902-1_16
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.
Keywords: Image registration, Meta-learning, Deep learning, Ultrasound
UCL classification: UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL
URI: https://discovery.ucl.ac.uk/id/eprint/10153271
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