Kok, TE;
Domingo, D;
Hassan, J;
Vuong, A;
Hordacre, B;
Clark, C;
Katrakazas, P;
(2022)
Resting-state Networks in Tinnitus: A Scoping Review.
Clinical Neuroradiology
10.1007/s00062-022-01170-1.
(In press).
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Abstract
Chronic subjective tinnitus is the constant perception of a sound that has no physical source. Brain imaging studies show alterations in tinnitus patients’ resting-state networks (RSNs). This scoping review aims to provide an overview of resting-state fMRI studies in tinnitus, and to evaluate the evidence for changes in different RSNs. A total of 29 studies were included, 26 of which found alterations in networks such as the auditory network, default mode network, attention networks, and visual network; however, there is a lack of reproducibility in the field which can be attributed to the use of different regions of interest and analytical methods per study, and tinnitus heterogeneity. Future studies should focus on replication by using the same regions of interest in their analysis of resting-state data, and by controlling adequately for potential confounds. These efforts could potentially lead to the identification of a biomarker for tinnitus in the future.
| Type: | Article |
|---|---|
| Title: | Resting-state Networks in Tinnitus: A Scoping Review |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1007/s00062-022-01170-1 |
| Publisher version: | https://doi.org/10.1007/s00062-022-01170-1 |
| Language: | English |
| Additional information: | © 2022 Springer Nature Switzerland AG. This article is licensed under a Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/). |
| Keywords: | Subjective tinnitus, Functional magnetic resonance imaging, Brain imaging, Neural networks, Auditory network, Review |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Neurosciences Dept UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10149250 |
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