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Patient Experience of Flunarizine for Vestibular Migraine: Single Centre Observational Study

Ur Rashid, SM; Sumaria, S; Koohi, N; Arshad, Q; Kaski, D; (2022) Patient Experience of Flunarizine for Vestibular Migraine: Single Centre Observational Study. Brain Sciences , 12 (4) , Article 415. 10.3390/brainsci12040415. Green open access

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Abstract

Vestibular migraine (VM) is a leading cause of episodic vertigo, affecting up to 1% of the general population. Despite established diagnostic criteria, there is currently no evidence-based approach for acute treatment of VM, with treatment recommendations generally extrapolated from studies on classical migraine headache. Several small-scale studies have identified flunarizine as a potentially effective prophylactic medication in VM. We conducted a single-centre observational service evaluation study exploring patient experiences of preventative medications over a 28-month period, including flunarizine, for control of VM symptoms. To compare patient experience of flunarizine with other medications, data from patients taking flunarizine were separately analysed. A total of 90% of VM patients taking flunarizine reported symptomatic improvement, compared to only 32% of patients on other medications. Whilst 50% of patients on flunarizine reported side effects. these were not deemed to outweigh the clinical benefits, with most patients deciding to continue treatment. Our data supports the use of flunarizine in VM.

Type: Article
Title: Patient Experience of Flunarizine for Vestibular Migraine: Single Centre Observational Study
Location: Switzerland
Open access status: An open access version is available from UCL Discovery
DOI: 10.3390/brainsci12040415
Publisher version: https://doi.org/10.3390/brainsci12040415
Language: English
Additional information: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
Keywords: Flunarizine, patient experience, prophylaxis, symptoms, vestibular migraine
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Movement Neurosciences
URI: https://discovery.ucl.ac.uk/id/eprint/10147783
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