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Integrating Evolutionary, Cultural, and Computational Psychiatry: A Multilevel Systemic Approach

Constant, Axel; Badcock, Paul; Friston, Karl; Kirmayer, Laurence J; (2022) Integrating Evolutionary, Cultural, and Computational Psychiatry: A Multilevel Systemic Approach. Frontiers in Psychiatry , 13 , Article 763380. 10.3389/fpsyt.2022.763380. Green open access

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Abstract

This paper proposes an integrative perspective on evolutionary, cultural and computational approaches to psychiatry. These three approaches attempt to frame mental disorders as multiscale entities and offer modes of explanations and modeling strategies that can inform clinical practice. Although each of these perspectives involves systemic thinking, each is limited in its ability to address the complex developmental trajectories and larger social systemic interactions that lead to mental disorders. Inspired by computational modeling in theoretical biology, this paper aims to integrate the modes of explanation offered by evolutionary, cultural and computational psychiatry in a multilevel systemic perspective. We apply the resulting Evolutionary, Cultural and Computational (ECC) model to Major Depressive Disorder (MDD) to illustrate how this integrative approach can guide research and practice in psychiatry.

Type: Article
Title: Integrating Evolutionary, Cultural, and Computational Psychiatry: A Multilevel Systemic Approach
Location: Switzerland
Open access status: An open access version is available from UCL Discovery
DOI: 10.3389/fpsyt.2022.763380
Publisher version: https://doi.org/10.3389/fpsyt.2022.763380
Language: English
Additional information: © 2022 Constant, Badcock, Friston and Kirmayer. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Keywords: cultural psychiatry, computational psychiatry, computational phenotyping, major depressive disorder (MDD), evolutionary psychiatry
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Imaging Neuroscience
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
URI: https://discovery.ucl.ac.uk/id/eprint/10147530
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