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The Effectiveness of E-Cigarettes for Smoking Cessation: A Comparison With Nicotine Replacement Therapy and No Use of Evidence-Based Cessation Aids in the German Population

Kotz, Daniel; Jackson, Sarah; Brown, James; Kastaun, Sabrina; (2022) The Effectiveness of E-Cigarettes for Smoking Cessation: A Comparison With Nicotine Replacement Therapy and No Use of Evidence-Based Cessation Aids in the German Population. Deutsches Ärzteblatt International , 119 (17) pp. 297-301. 10.3238/arztebl.m2022.0162. Green open access

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Abstract

BACKGROUND: Our primary aim was to assess-in the German population-the effectiveness of e-cigarettes (ECs; with or without nicotine), nicotine replacement therapy (NRT), and no use of evidence-based aids in smoking cessation. METHODS: Analysis of cross-sectional data from a representative survey of the population (age 14‒96 years) conducted in 2016‒2021. All current smokers and recent ex-smokers (<12 months since quitting) who had made ≥1 attempt to quit in the past 12 months (n = 2740) were included. They were asked about use of cessation aids in their most recent quit attempt and their current smoking status. RESULTS: 239 respondents had used ECs, 168 NRT, and 2333 no aid. After adjustment for potential confounders, the odds of abstinence were 1.78 times higher for smokers who had used ECs in their quit attempt than in the group that had used no aids (95% confidence interval [1.09; 2.92]; p = 0.02) and 1.46 times higher than in the NRT group ([0.68; 3.13]; p = 0.34, Bayes Factor = 1.26). Compared with the unaided group, the odds of abstinence were 2.34 times higher ([1.21; 4.53]; p = 0.01) in the subgroup using ECs with nicotine and 1.48 times higher ([0.68; 3.26]; p = 0.33) in the subgroup using ECs without nicotine. The unadjusted abstinence rates in people who had started their quit attempt >6 months earlier were 15.6% [9.4; 23.8] in the ECs group and 13.8% [7.3; 22.9] in the NRT group. CONCLUSION: In Germany, use of ECs in an attempt to quit smoking is associated with a higher rate of abstinence than attempting to quit unaided.

Type: Article
Title: The Effectiveness of E-Cigarettes for Smoking Cessation: A Comparison With Nicotine Replacement Therapy and No Use of Evidence-Based Cessation Aids in the German Population
Open access status: An open access version is available from UCL Discovery
DOI: 10.3238/arztebl.m2022.0162
Publisher version: https://doi.org/10.3238/arztebl.m2022.0162
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Behavioural Science and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/10146262
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